Tools for Comparative Genomics

VISTA is a comprehensive suite of programs and databases for comparative analysis of genomic sequences. There are two ways of using VISTA - you can submit your own sequences and alignments for analysis (VISTA servers) or examine pre-computed whole-genome alignments of different species.

 

Submit Your Sequences

mVISTA

mVISTA tool thumbnail
  • mVISTA

    Align and compare your sequences from multiple species

  • rVISTA

    Locate regulatory sequences in your data using comparative sequence analysis and transcription factor binding site search.

  • GenomeVISTA

    Compare your sequences against whole-genome assemblies.

  • wgVISTA

    Align pair of sequences up to 10Mb long (finished or draft) including microbial whole-genome assemblies.

 

Precomputed Alignments

VISTA Browser

VISTA Browser tool thumbnail
  • VISTA Browser

    Examine pre-computed pairwise and multiple alignments of whole genome assemblies.

  • VISTA-Point

    Access complete data and visual presentation of pairwise and multiple alignments of whole genome assemblies.

  • Whole Genome rVISTA

    Identify transcription factor binding sites that are conserved between species and over-represented in upstream regions of groups of genes.

  • Microbial Genomes

    Access pre-computed full scaffold alignments for microbial genomes through the VISTA component of IMG.

 

Updates

August 2010
Added the whole-genome multiple alignment of five primates: Human, Chimpanzee, Orangutan, Rhesus, Marmoset.
Added the Human Feb. 2009 - Mouse Jul. 2007 pairwise alignment.

April 2010
Added the whole-genome multiple alignment of five plants: Sorghum, Maize, Rice, B. distachyon, S. italica.

February 2010
OpenHelix released a new VISTA tutorial.

Read the VISTA guest post at the blog on February 16, 2010.

Vista News Archive

 

 

Enhancer DB

Enhancer DB iconExperimentally validated human noncoding fragments with gene enhancer activity as assessed in transgenic mice. http://enhancer.lbl.gov/
 

JGI Genome Portal

Genome Portal iconFind VISTA alignments for a number of genomes sequenced in the Department of Energy Joint Genome Institute http://genome.jgi-psf.org/